Temperature Range for Control

The normal full range of control for each of the temperature controllers is -55 °C to +105 °C ± 0.02 °C. If one specifies the extended temperature version available for the TLC 40, TLC 42, or TLC 50 (place a /E after the model number), then the full control range is -55 °C up to +150 °C ± 0.02 °C.

approximate temperatures achievable under various conditions TLC 40 TLC 42 TLC 50 CD 250 TURRET 400 FLASH 200 FLASH 300 LC 600
highest temperature /E option 150 150 150 -- -- -- -- --
normal highest temperature 105 105 105 105 105 105 105 105
in the open, no dry gas flow 5 5 5 5 5 5 5 5
exposed but with dry gas flow -10 -10 -10 -10 -10 -10 -10 -10
enclosed in dry environment, 0 degree circulating fluid -25 -25 -25 -25 -25 -25 -25 -25
with windows, cold circulating fluid, some added insulation -40 -40 -40 -40 -- -40 -40 --
with windows, very cold circulating fluid, lots of added insulation -55 -55 -55 -- -- -55 -55 --


Achievable temperatures:

highest temperature /E option – Special versions of the TLC 40, TLC 42, or TLC 50 can be made to operate above 105 °C. This requires special firmware in the microcomputer of the temperature controller and special changes that replace or isolate heat sensitive components under the cuvette. Temperatures up to 150 °C may be obtained, although the upper range of temperatures should not be used for extended periods of time. Operation substantially above boiling temperatures requires shutting down the cooling fluid circulation, limiting some features of control.
normal highest temperature – All sample holders will heat to at least 105 °C. Unless the extended temperature option is installed, the controller limits operation to this temperature to prevent damage to internal components.
in the open, no dry gas flow – Unless special care is taken, operation at or below the dew point temperature of the room (estimated here to be 5 °C) will result in condensation on the cuvette windows.
exposed but with dry gas flow – Most cuvette holders are provided with a dry gas purge option that greatly limits condensation when working in an exposed environment, permitting operation down to about -10 °C.
enclosed in dry environment, 0 degree circulating fluid – When used inside of a spectrophotometer that can be purged with dry gas, no condensation will occur, and much lower temperatures may be reached. For a sample holder mounted in a spectrometer, simply providing dry gas flow to the holder will satisfactorily prevent condensation. Ice water is a convenient circulating fluid for most low temperature work.
with windows, cold circulating fluid, some added insulation – Very cold operation requires the use of optical windows to thermally insulate the cuvette. We recommend the windowed jackets WJ-40, WJ-50 and WJ-200 on the TLC 40, TLC 50 and FLASH 200, respectively for this purpose. The CD 250 can also be provided with windows that mount directly on the sample holder. Very low temperatures also require the use chilled cooling fluid to remove heat from the Peltier unit. Typically one uses methanol or methanol-water mixtures within about 25 °C of the temperature you wish to achieve. Any additional insulation provided by the user (such as a layer of bubble wrap, for example) can speed temperature equilibration.
with windows, very cold circulating fluid, lots of added insulation – We have only tested our sample holders down to -40 °C, but lower temperatures can be achieved with special care. Please contact us for suggestions on how to work at these very low temperatures.


Probe Temperature Range
The TC 125 and TC 425 temperature controllers accept standard 400 and 500 Series thermistor probes. These probes may be obtained from Yellow Springs Instrument Company (ysi.com) or Cole Parmer (coleparmer.com). Standard 400 Series temperature probes will measure the temperature within ±0.1 °C over the range of 0.0 to 70.0 °C. The probe will operate over the full range of -55 °C to +105 °C, but an individual probe will need to be calibrated by the user outside of the 0.0 to 70.0 °C range. The 500 Series probes are less standardized and will require calibration by the user. 500 Series probes may be convenient, because they are available in very small diameters.